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Jeffrey Scott McLean, PhD, PI https://www.jsmcleanlab.com/lab-members/2019/3/11/haauknee-slabs-az-sntak-n7ryd monthly 0.5 2026-01-02 https://www.jsmcleanlab.com/lab-members/2019/3/11/zrmanja-falls-croatia-f3exm-j54cg monthly 0.5 2023-09-22 https://www.jsmcleanlab.com/lab-members/allison monthly 0.5 2026-03-04 https://www.jsmcleanlab.com/lab-members/tanvi-ranganathan monthly 0.5 2023-03-23 https://www.jsmcleanlab.com/lab-members/amay-bansal monthly 0.5 2023-03-19 https://www.jsmcleanlab.com/lab-members/elissa monthly 0.5 2023-03-19 https://www.jsmcleanlab.com/collabandalumni daily 0.75 2022-09-20 https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590194516505-Q8O9FDB9G299FISX8RQ9/UCSD.jpg Collaborators and Alumni https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590193796284-NVFKNKC64KHJ1YJ7370S/Colgate.png Collaborators and Alumni https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590193556058-2OMWBJ20EKKCADTIY3PN/PNNL.png Collaborators and Alumni https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590194908039-U98Q7ZAX9YIRYOGVNT3N/wsu.jpg Collaborators and Alumni https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590193498447-HA538IQT3JPS2ATQ8R50/JCVI.png Collaborators and Alumni https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590193705219-BC5AKI5AWP46ITBP5IV3/Forsyth.png Collaborators and Alumni https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590193895661-GH83DRREXN4M33YB2EXZ/Fred+Hutch.jpg Collaborators and Alumni https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590194650264-KNGH2449CQ0XDF0K7BXN/SDSU.png Collaborators and Alumni https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590194083037-R18AZDWYVT35SD3XQ99R/UCLA.png Collaborators and Alumni https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590194186265-Y99U2B3OZZNVP7NU7KNK/UTSA.gif Collaborators and Alumni https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590194459304-SVKGX8CE48PW2BK2ZMC4/USC.png Collaborators and Alumni https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590194732789-DIFSYMSYS2DAPU4GP311/UofM.png Collaborators and Alumni https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590195019246-74LJK2KV9056HRVOV3ZO/rochester.jpg Collaborators and Alumni https://www.jsmcleanlab.com/press daily 0.75 2026-03-02 https://www.jsmcleanlab.com/press/dr-jeffrey-mclean-appointed-interim-director-microbial-interactions-amp-microbiome-center-oct-2025- monthly 0.5 2026-03-02 https://www.jsmcleanlab.com/press/celine-atkinson-named-2025-school-of-dentistry-magnuson-scholar monthly 0.5 2025-12-31 https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/487700da-5ff7-404d-81f4-82d8d87637e6/Celine-Atkinson-240x300.jpg In the Press - Celine Atkinson Named 2025 School of Dentistry Magnuson Scholar - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/4918927f-82e2-4a0c-92fa-9a28ec1a9a21/Celine+Cert+Dental+1+Cropped.jpg In the Press - Celine Atkinson Named 2025 School of Dentistry Magnuson Scholar - Jeff McLean, Celine Atkinson and Dean Ritter https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/cb2ab906-73bd-4abb-b186-f51c36b77343/Big+Group+5+Edited.jpg In the Press - Celine Atkinson Named 2025 School of Dentistry Magnuson Scholar - Make it stand out Magnuson Scholars for 2025 , their mentors and Deans of UW Schools https://www.jsmcleanlab.com/press/uw-periodontal-researchers-discover-mirrored-shift-in-oral-microbiome-caused-by-inflammation monthly 0.5 2025-12-31 https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/eee9e7de-899a-46cb-9636-837c5516d3aa/Fig.+6.jpg In the Press - UW periodontics team led by Kris Kerns discover non-localized effect of inflammation (PNAS) - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://www.jsmcleanlab.com/press/the-oral-microbiome-diversity-biogeography-and-human-health monthly 0.5 2023-09-22 https://www.jsmcleanlab.com/press/genetic-manipulation-of-patescibacteria-formerly-saccharibacteria-provides-mechanistic-insights-into-epibiotic-lifestyle monthly 0.5 2023-09-25 https://www.jsmcleanlab.com/press/mice-and-their-microbiomes-may-hold-the-key-to-protecting-astronauts-from-the-effects-of-microgravity monthly 0.5 2023-09-14 https://www.jsmcleanlab.com/press/mcleanlab-to-expand-upon-research-into-variation-in-gingival-responses-l monthly 0.5 2023-07-19 https://www.jsmcleanlab.com/press/dr-mclean-named-interim-co-director-of-cmist monthly 0.5 2023-03-22 https://www.jsmcleanlab.com/press/forsyth-researchers-reveal-that-oral-tm7-bacteria-may-protect-humans-from-pathogenic-bacteria-cell-host-amp-microbe monthly 0.5 2022-01-07 https://www.jsmcleanlab.com/press/acquisition-of-the-arginine-deiminase-system-benefits-epiparasitic-saccharibacteria-and-their-host-bacteria-in-a-mammalian-niche-environment monthly 0.5 2022-01-07 https://www.jsmcleanlab.com/press/uw-researchers-reveal-new-aspects-of-gum-disease-and-bodys-protective-response monthly 0.5 2022-09-20 https://www.jsmcleanlab.com/press/replicating-diseased-communities-with-modified-shi-media monthly 0.5 2022-09-20 https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1608051749099-9NDS0BHT3SWXE6G6PPJY/omi12323-fig-0002-m.jpg In the Press - Replicating Diseased Communities with Modified SHI Media *Number one downloaded paper from Wiley Publishing 2022! https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1608051646007-GRKCHV8WHSF6DL7CZQRV/modified+Shi+image.jpg In the Press - Replicating Diseased Communities with Modified SHI Media *Number one downloaded paper from Wiley Publishing 2022! Developing a laboratory model of oral polymicrobial communities is essential for in vitro studies of the transition from healthy to diseased oral plaque. Here, we systematically modified SHI medium components to investigate the impacts of varying nutrients and develop a medium capable of supporting a specific disease-state subgingival community. Biofilms grown in subSHI-v1 medium retained high diversity closest to the source inoculum and maintained greater proportions of many gram-negative species of interest from the subgingival periodontal pocket (including members of the genera Prevotella and Treponema, and the Candidate Phyla Radiation phylum Saccharibacteria) Lamont, E.I., Gadkari, A., Kerns, K.A., To, T.T., Daubert, D., Kotsakis, G., Bor, B., He, X., McLean, J.S. Modified SHI medium supports growth of a disease-state subgingival polymicrobial community in vitro. Molecular Oral Microbiology. 2020 Nov 11. https://doi.org/10.1111/omi.12323 PubMed PMID: 33174294 https://www.jsmcleanlab.com/press/biosensors-in-bacteria-twim-episode-222 monthly 0.5 2022-01-07 https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1598991854407-U9BJNRGWEABX4SA3UN13/Screen+Shot+2020-09-01+at+1.23.49+PM.png In the Press - Our work on nano-sized parasitic bacteria covered in TWiM episode 222 https://www.jsmcleanlab.com/press/humans-are-inhabited-by-a-broad-diversity-of-nano-sized-bacteria-with-tiny-genomes monthly 0.5 2022-01-07 https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1595456415836-3QV599YBEY5M5YZMO9RI/RAXML_105_BEST_MIN-NOLABEL_cado1CELL_V5-01.png In the Press - Humans are inhabited by a broad diversity of nano-sized bacteria with tiny genomes. https://www.jsmcleanlab.com/press/science-news monthly 0.5 2020-05-22 https://www.jsmcleanlab.com/press/blog-post-title-one-jyezy monthly 0.5 2021-04-25 https://www.jsmcleanlab.com/press/blog-post-title-three-9s7mj monthly 0.5 2021-04-25 https://www.jsmcleanlab.com/press/blog-post-title-four-7yrz2 monthly 0.5 2022-01-07 https://www.jsmcleanlab.com/press/sharing-and-community-curation-of-mass-spectrometry-data-with-global-natural-products-social-molecular-networking monthly 0.5 2020-05-22 https://www.jsmcleanlab.com/services-1 daily 0.75 2025-12-31 https://www.jsmcleanlab.com/home daily 1.0 2025-12-30 https://www.jsmcleanlab.com/pager daily 0.75 2025-12-30 https://www.jsmcleanlab.com/oral-microbiome daily 0.75 2020-05-24 https://www.jsmcleanlab.com/deposited-genomes daily 0.75 2024-05-17 https://www.jsmcleanlab.com/tm7saccharibacteria daily 0.75 2025-12-30 https://www.jsmcleanlab.com/bioinfoanddata daily 0.75 2025-12-30 https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590187393096-9U4NZBTCX28Z46J3VF87/dryad-logo.png Bioinformatics & Public Data https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590166986407-YQZV8HIAPRL41D7EAXKM/github-logo.jpg Bioinformatics & Public Data https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590086572578-5HJYN9SR0VQDSWPX78BT/Screen+Shot+2020-05-21+at+11.42.26+AM.png Bioinformatics & Public Data https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590169793077-USOEMZMKF8FAG77YU1LT/Screen+Shot+2020-05-22+at+10.49.25+AM.png Bioinformatics & Public Data https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590167378506-RA9AM91OF55ZWBS74N5J/WGS_pic.jpg Bioinformatics & Public Data https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590169654419-8Z27ZZ5454LY980GYZI1/Heatmap_pic.jpg Bioinformatics & Public Data https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590187754925-DW62IT41VF4PBPIDNG4W/Screen+Shot+2020-05-22+at+3.49.03+PM.png Bioinformatics & Public Data https://www.jsmcleanlab.com/perio daily 0.75 2024-03-29 https://www.jsmcleanlab.com/protocols daily 0.75 2023-04-21 https://www.jsmcleanlab.com/all-publications daily 0.75 2026-03-01 https://www.jsmcleanlab.com/contact daily 0.75 2020-05-20 https://www.jsmcleanlab.com/join-our-lab daily 0.75 2020-05-21 https://www.jsmcleanlab.com/about daily 0.75 2020-09-06 https://images.squarespace-cdn.com/content/v1/5eac4ca67214b127262c77be/1590335547050-E76YJ3GQYB0CMB9PG5M6/montlake.jpg About - About Our Lab Dr. McLean received his PhD at the University of Southern California with Kenneth Nealson and his MSc at the University of Guelph in Canada with Dr. Terry Beveridge. Dr. McLean’s research career at the Pacific Northwest National Laboratory, the J. Craig Venter Institute and now at the University of Washington School of Dentistry has been primarily devoted to developing innovative methodologies, tools and new genomic based approaches to study microbial interactions within oral biofilm communities. Currently, he is funded as a PI on active NIH R01 grants that employ next generation sequencing techniques such as single cell genomics and metatranscriptomics to characterize the microbial processes that lead to oral inflammation and disease as well as maintain the health of the human oral microbiome. 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