Kristopher A. Kerns, PhD, MPH
Education:
PhD, Oral Health Sciences, University of Washington School of Dentistry
MCH, Epidemiology, University of Washington School of Public Health
MPH-D, A.T. Still University, College of Graduate Health Sciences
BS, University of Puget Sound
Research Interests:
Microbiome Systems Biology
Omics and Bioinformatics
Host-Bacterial Interactions
Publications:
Bedree JK, Kerns KA, Chen T, Lima BP, Liu G, Ha P, Shi J, Pan HC, Kim JK, Tran L, Minot SS, Hendrickson EL, Lamont EI, Schulte F, Hardt M, Stephens D, Patel M, Kokaras A, Stodieck L, Shirazi-Fard Y, Wu B, Kwak JH, Ting K, Soo C, McLean JS, He X, Shi W. Specific host metabolite and gut microbiome alterations are associated with bone loss during spaceflight. Cell Rep. 2023 May 30;42(5):112299. doi: 10.1016/j.celrep.2023.112299. Epub 2023 Apr 19. PMID: 37080202; PMCID: PMC10344367.
Liu J, Utter DR, Nie J, Kerns KA, Lamont EI, Hendrickson EL, Wang X, McLean JS, He X, Bor B. Draft Genome Sequences of Nine "Candidatus Nanosynbacter sp. HMT-352" Strains Cultured from the Human Oral Cavity. Microbiol Resour Announc. 2022 Aug 18;11(8):e0040322. doi: 10.1128/mra.00403-22. Epub 2022 Jul 27. PMID: 35894623; PMCID: PMC9387224.
Hendrickson EL, Bor B, Kerns KA, Lamont EI, Chang Y, Liu J, Cen L, Schulte F, Hardt M, Shi W, He X, McLean JS. Transcriptome of Epibiont Saccharibacteria Nanosynbacter lyticus Strain TM7x During the Establishment of Symbiosis. J Bacteriol. 2022 Sep 20;204(9):e0011222. doi: 10.1128/jb.00112-22. Epub 2022 Aug 17. PMID: 35975994; PMCID: PMC9487520.
Nie J, Utter DR, Kerns KA, Lamont EI, Hendrickson EL, Liu J, Wu T, He X, McLean J, Bor B. Strain-Level Variation and Diverse Host Bacterial Responses in Episymbiotic Saccharibacteria. mSystems. 2022 Apr 26;7(2):e0148821. doi: 10.1128/msystems.01488-21. Epub 2022 Mar 28. PMID: 35343799; PMCID: PMC9040727.
Bamashmous S, Kotsakis GA, Kerns KA, Leroux BG, Zenobia C, Chen D, Trivedi HM, McLean JS, Darveau RP. Human variation in gingival inflammation. Proc Natl Acad Sci U S A. 2021 Jul 6;118(27):e2012578118. doi: 10.1073/pnas.2012578118. PMID: 34193520; PMCID: PMC8271746.
Lamont EI, Gadkari A, Kerns KA, To TT, Daubert D, Kotsakis G, Bor B, He X, McLean JS. Modified SHI medium supports growth of a disease-state subgingival polymicrobial community in vitro. Mol Oral Microbiol. 2021 Feb;36(1):37-49. doi: 10.1111/omi.12323. Epub 2020 Dec 3. PMID: 33174294; PMCID: PMC7984074.
McLean JS, Bor B, Kerns KA, Liu Q, To TT, Solden L, Hendrickson EL, Wrighton K, Shi W, He X. Acquisition and Adaptation of Ultra-small Parasitic Reduced Genome Bacteria to Mammalian Hosts. Cell Rep. 2020 Jul 21;32(3):107939. doi: 10.1016/j.celrep.2020.107939. PMID: 32698001; PMCID: PMC7427843.
An JY, Kerns KA, Ouellette A, Robinson L, Morris HD, Kaczorowski C, Park SI, Mekvanich T, Kang A, McLean JS, Cox TC, Kaeberlein M. Rapamycin rejuvenates oral health in aging mice. Elife. 2020 Apr 28;9:e54318. doi: 10.7554/eLife.54318. PMID: 32342860; PMCID: PMC7220376.
Articles:
Kerns, KA “Anti-Fluoridation Efforts Threaten Oral Health Protections for Children in Washington State”. 2019. Vol. 35: Oral Health, PART II: Sustainable Oral Health Innovations to Reach Underserved Communities. University of Washington, School of Public Health, Northwest Bulletin Family and Child Health. https://depts.washington.edu/nwbfch/washington-community-water-fluoridation
Kerns, KA “What You Should Know About Silver Diamine Fluoride”. 2019. Vol. 35: Oral Health, PART III: New Ways to Decrease Tooth Decay. University of Washington, School of Public Health, Northwest Bulletin Family and Child Health. https://depts.washington.edu/nwbfch/silver-diamine-fluoride-SDF-for-children-cavitiesContact
Bioinformatic Resources:
Contact Information:
Address: 1959 NE Pacific St Box 357444 Seattle, WA 98195-7444
Phone: 206-616-2614
Email: kkerns85@uw.edu
“An investment in knowledge pays the best interest.” - Ben Franklin